实现高水平科技自立自强是中国共产党在科学技术事业方面的重要思想和发展方向，这一行动指南以马克思主义科技观为理论逻辑，始终发挥着塑造中华优秀传统文化逻辑精髓的重要作用，与科技帝国主义垄断控制的现实逻辑建构起理解高水平科技自立自强的基本思维框架。大变局时代拓展我国科技发展的嵌入领域、形塑着我国科技发展的奋斗目标、重构我国科技发展的战略布局。需要正视的是，实现高水平科技自立自强不是一蹴而就的，大变局时代下我国应着重向倡导人类命运共同体观念、坚持走中国特色自主创新道路、提升数字科技全球竞争力这三个方向转变。

The realization of high-level scientific and technological self-reliance and self-improvement is an important idea and development direction of the CPC in the cause of science and technology, and this guide to action, based on the theoretical logic of the Marxist outlook on science and technology, has always played an important role in shaping the logic and essence of the excellent traditional Chinese culture, and has constructed a basic frame of mind for understanding high-level scientific and technological self-reliance and self-improvement in conjunction with the reality of the logic of the monopoly of scientific and technological imperialist control. The era of great changes has expanded the embedded field of China's scientific and technological development, shaped the goal of China's scientific and technological development, and reconstructed the strategic layout of China's scientific and technological development. It is important to note that realizing high-level self-reliance in science and technology cannot be achieved overnight, and under the era of great changes, China should focus on the three directions of advocating the concept of a community of human destiny, adhering to the path of independent innovation with Chinese characteristics, and enhancing the global competitiveness of digital science and technology.