Modern China has fallen into a holistic crisis, and the economic, political, cultural, military and other aspects of China have fallen behind those of the west. This paper, from the holistic crisis of China, summarizes the historical experience and lessons, and believes that China's crisis must be solved as a whole. The holistic view of Marxism provides a theoretical basis for solving the Chinese crisis as a whole, and also provides a holistic perspective for the solution of China's crisis, which is of great significance for the settlement of major historical tasks in modern China.