Summary of physical activity on depression focused on physical activity to reduce depression,the relationship between depression and physical activity in a particular field,as well as the neurotrophic hypothesis of antidepressant actions of exercise for research. In this article,you can observe the depression from the perspective of Psychology,Neurophysiology,Movement,the Labor Theory of Evolution and so on. Also, the physical activity related to the treatment of depression is defined clearly. Previous relevant studies were reviewed, and we should keep that clinical antidepressant drug treatment with a combination of physical activity to cure the depression effectively.